RESOURCES

Nervous system design, in plain language.

Articles, videos, founder talks, research summaries and stories from the people using these products.

Heliyon / Elsevier
Sensory Processing

Comfort evaluation and physiological effects/autonomic nervous system response of inflatable deep pressure vest in reducing anxiety

A 2024 experimental study measuring pressure, touch and mobility comfort alongside pulse-rate changes from an inflatable deep-pressure vest.

Heliyon / Elsevier
Frontiers in Integrative Neuroscience
Sensory Processing

Physiological and behavioral differences in sensory processing: a comparison of children with Autism Spectrum Disorder and Sensory Modulation Disorder

An original research study comparing sympathetic nervous system responses to sensory challenges across three groups of children, showing that sensory response is heterogeneous rather than universal.

Frontiers in Integrative Neuroscience
Psychoneuroendocrinology / ScienceDirect (Elsevier)
Regulation

Affect regulation and allostatic load over time

Research using the concept of allostatic load — the cumulative wear and tear associated with repeated or chronic demands on the body's adaptive systems — to explain why accumulated stressors matter, not just one isolated event.

Psychoneuroendocrinology / ScienceDirect (Elsevier)
NIH / National Center for Complementary and Integrative Health (NCCIH)
Regulation

Stress

An NIH overview of stress as a normal physical and emotional response to challenge — how the body mobilizes through stress-response systems, and how recovery processes help it move back toward baseline once a challenge passes.

NIH / National Center for Complementary and Integrative Health (NCCIH)
Building and Environment / ScienceDirect (Elsevier)
Warmth

Individual difference in thermal comfort: A literature review

A major literature review finding substantial individual differences in preferred, neutral and comfortable temperatures — showing that thermal comfort isn't fixed, and even the same person's preference can change from moment to moment.

Building and Environment / ScienceDirect (Elsevier)
NIH / National Center for Complementary and Integrative Health (NCCIH)
Regulation

Relaxation Techniques: What You Need To Know

NCCIH describes the relaxation response as the physiological counterpart to the stress response — associated with changes such as slower breathing, lower blood pressure and reduced heart rate.

NIH / National Center for Complementary and Integrative Health (NCCIH)
Frontiers in Neuroscience
Regulation

Neurovisceral Integration: A New Perspective on the Pathophysiology of Post-Traumatic Stress Disorder

Research on autonomic regulation emphasizing flexibility — the ability to adjust physiological responses as circumstances change, with access to activation when it's useful and recovery when it's no longer needed.

Frontiers in Neuroscience
PubMed
ADHD

Sensory Processing in Individuals With ADHD Compared With Control Populations: A Systematic Review and Meta-Analysis

A 2025 systematic review and meta-analysis finding significantly greater sensory atypicalities in people with ADHD across sensory sensitivity, avoiding, low registration and seeking.

PubMed
Frontiers in Psychology
Regulation

Interoception, Vagal Tone, and Emotional Regulation: A Review of Current Evidence and Directions for Future Research

A systematic review of the relationships among interoception, cardiac vagal tone and emotion regulation — supporting the broader idea that sensing what's happening inside the body is connected to how people understand and regulate their internal states.

Frontiers in Psychology
PubMed
Autism

Autism spectrum disorder in the scope of tactile processing

A peer-reviewed review of tactile-processing differences in autism, supporting the broader point that touch and other sensory inputs can be experienced very differently from person to person.

PubMed
Temperature / Taylor & Francis (PubMed Central)
Warmth

Responses of the hands and feet to cold exposure

A physiological review explaining how cold exposure produces strong vasoconstriction in the extremities — describing the hands and feet as key thermoregulatory regions and examining how local cold affects tactile sensitivity and manual function.

Temperature / Taylor & Francis (PubMed Central)
Building and Environment / ScienceDirect (Elsevier)
Warmth

Physical and physiological differences in thermal comfort and regulation among older adults: A systematic review

A 2025 systematic review of 141 studies finding physiological differences between older and younger adults that can affect thermoregulation — including lower skin temperatures in cold conditions, particularly at the extremities, among older adults.

Building and Environment / ScienceDirect (Elsevier)
UC Berkeley Center for the Built Environment
Warmth

Comfort and Work Performance in a Low-Power Personal Comfort System

Research finding that local thermal comfort at the hands, feet and face can strongly influence overall thermal comfort — testing localized heating and cooling rather than changing the temperature of an entire environment.

UC Berkeley Center for the Built Environment
Ageing Research Reviews / ScienceDirect (Elsevier)
Warmth

Thermal sensitivity in the elderly: A review

A review finding that aging is associated with reduced thermal sensitivity, with changes especially pronounced in the limbs — discussing possible contributors such as skin, thermoreceptor density, blood flow and peripheral nerve changes.

Ageing Research Reviews / ScienceDirect (Elsevier)
UC Berkeley Center for the Built Environment
Warmth

Advanced Personal Comfort Systems Development and Testing

UC Berkeley research on Personal Comfort Systems — giving individuals localized ways to heat or cool themselves — describing improved comfort across a wider range of ambient temperatures when occupants can control their immediate thermal environment.

UC Berkeley Center for the Built Environment
NIH / National Center for Complementary and Integrative Health (NCCIH)
Stress

Stress

A clear NIH overview of the body's stress response and recovery — how activation is a normal part of responding to challenge, and how recovery helps the body move back toward a more manageable state.

NIH / National Center for Complementary and Integrative Health (NCCIH)
PubMed
Dialysis Treatments

Clinical Outcomes of Patients undergoing Hemodialysis with Cool versus Standard Dialysate: A Systematic Review and Meta-Analysis

A review finding that cooler dialysate may offer clinical benefits in some situations but can also increase patient discomfort and lower body temperature — showing that temperature and comfort are real parts of the dialysis experience.

PubMed
Frontiers in Behavioral Neuroscience
Regulation

The Biology of Stress and the Neurobiology of Stress-Related Disorders

A neuroscience review describing stress as a coordinated biological response involving interacting brain, autonomic, endocrine and immune systems — and how chronic stress can affect multiple systems rather than existing only as a mental or emotional experience.

Frontiers in Behavioral Neuroscience
Scandinavian Journal of Occupational Therapy
Sensory Processing

Defining sensory modulation: A review of the concept and a contemporary definition for application by occupational therapists

A peer-reviewed occupational therapy review describing sensory modulation — the nervous system's ability to regulate and process sensory input — and how it shapes a person's ability to respond behaviorally.

Scandinavian Journal of Occupational Therapy
Psychology Research and Behavior Management
Sensory Processing

Interoception in Autism: A Narrative Review of Behavioral and Neurobiological Data

A 2024 review from researchers affiliated with USC's Brain and Creativity Institute examining differences in interoceptive processing — our perception of internal signals like heartbeat and temperature — in autism.

Psychology Research and Behavior Management
Neuropsychology Review
Sensory Processing

Coactivation of Autonomic and Central Nervous Systems During Processing of Socially Relevant Information in Autism Spectrum Disorder: A Systematic Review

A 2024 systematic review examining differences in autonomic and central nervous system responses between autistic and typically developing people.

Neuropsychology Review
Pediatric Research / Nature
Sensory Processing

Sensory Processing in Autism: A Review of Neurophysiologic Findings

A peer-reviewed review of the neurophysiology of sensory processing in autism across auditory, tactile and visual input, drawing on EEG, MEG and fMRI research.

Pediatric Research / Nature
American Occupational Therapy Association (AOTA)
Sensory Processing

Using a capstone experience to enhance inclusion and accessibility for individuals with sensory processing differences

AOTA discusses how sensory processing and integration differences can create barriers to participation in everyday community environments.

American Occupational Therapy Association (AOTA)
Occupational Therapy International / Wiley
Sensory Processing

The Immediate Effects of Deep Pressure on Young People with Autism and Severe Intellectual Difficulties: Demonstrating Individual Differences

A study evaluating immediate responses to deep pressure in young people with autism and severe intellectual disabilities, finding that individual responses vary and should be carefully monitored.

Occupational Therapy International / Wiley
Nature Reviews Neuroscience
Regulation

Allostasis and the human brain: Integrating models of stress from the social and life sciences

A review of allostasis — how the body maintains stability through change by continually adjusting physiology in anticipation of and response to changing demands, rather than holding every system at one fixed setting.

Nature Reviews Neuroscience
Journal of Personality and Social Psychology / APA PsycNet
Regulation

Emotion Regulation and Memory: The Cognitive Costs of Keeping One's Cool

Research distinguishing between emotion-regulation strategies used earlier in an emotional response and those used after a response is already underway, showing that when someone intervenes can affect the experience and effort involved.

Journal of Personality and Social Psychology / APA PsycNet
ASHRAE
Warmth

ASHRAE Handbook — Thermal Comfort

ASHRAE's thermal comfort guidance describing comfort as the result of interacting environmental and personal factors rather than room temperature alone — noting that local discomfort at different body regions can affect overall comfort.

ASHRAE
PubMed / NCBI
Freedom

The impact of assistive living technology on perceived independence of people with a physical disability in executing daily activities: a systematic literature review

A systematic literature review examining how assistive living technology affects perceived independence for people with physical disabilities — identifying themes such as feeling enabled, choice and control, security, time alone, feeling less needy, and participation in daily activities.

PubMed / NCBI
NIH / NCCIH
Anxiety

Mind and Body Approaches for Stress and Anxiety: What the Science Says

An NIH summary of the evidence around approaches that help people manage stress and anxiety, grounding a plain-language view of regulation and environment.

NIH / NCCIH
National Cancer Institute
Cancer Care

Cancer Fatigue

NCI explains how cancer and cancer-treatment fatigue can interfere with ordinary day-to-day activities and physical function.

National Cancer Institute
World Health Organization
Recovery

Rehabilitation

WHO describes rehabilitation as helping people optimize functioning, remain as independent as possible and participate in meaningful daily life after illness, injury or changes in health.

World Health Organization
NIH / PMC
Caregiving

How assistive technology use by individuals with disabilities impacts their caregivers: A systematic review of the research evidence

A review suggesting that tools which increase a care recipient's ability to do things more independently may reduce some of the physical and emotional effort required from informal caregivers.

NIH / PMC
National Institute on Aging (NIA)
Aging

Maintaining mobility and preventing disability are key to living independently as we age

NIA connects mobility and physical function with independent living and the ability to continue everyday activities as people age.

National Institute on Aging (NIA)
NIH / PMC
Sleep

Sleep and thermoregulation

A review of the two-way relationship between sleep and body temperature, supporting the idea that thermal comfort matters around sleep — not simply more warmth, but the right thermal state for the individual.

NIH / PMC

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